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A-769662 (CAS 844499-71-4)




Product specification

Formula: C20H12N2O3S
MW: 360.39
Purity: >=98%
Appearance: Off-white solid
Solubility: 100 mM in DMSO and to 10 mM in ethanol.
Storage: +4˚C.
CAS Number: 844499-71-4
Synonyms: A 769662
Cat.number: VD-ESA-0014

Product Description

A 769662 (CAS 844499-71-4) is a potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo. Also inhibits proliferation of mesenchymal stem cells, and impedes reprogramming of mouse embryonic fibroblasts to iPSCs.



Product References
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