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AICAR (CAS 2627-69-2)

Product specification

Formula: C9H14N4O5
MW: 258.23
Purity: >99%
Appearance: White solid.
Solubility: 75 mM in water and to 75 mM in DMSO
Storage: -20°C.
CAS Number: 2627-69-2
Synonyms: Aicar, Acadesine, Aica-riboside, NSC-105823, NSC105823, N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Cat.number: VD-ESA-0015

Product Description

AICAR (CAS 2627-69-2)  a cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCs in vitro.

Product References
1. Giri et al (2004)  J.Neurosci. 24 479.
2. Kanazawa et al (2007) BMC Cell Biol. 8 51.
3. Giri et al (2008) J.Neurochem. 105 1820.
4. Wu et al (2011) Int.J.Artif.Organs. 34 1128.