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CFM 1571 hydrochloride (CAS 1215548-30-3)




Product specification

Formula: C23H28N4O3.HCl
MW: 444.95
Purity: >99%
Appearance: White crystalline solid.
Solubility: 100 mM in water and to 100 mM in DMSO.
Storage: +4˚C.
CAS Number: 1215548-30-3
Synonyms: CFM 1571 hydrochloride
Cat.number: VD-ESA-0017

Product Description

CFM 1571 hydrochloride (CAS 1215548-30-3) is a soluble guanylyl cyclase (sGC) activator (EC50 = 5.49 μM). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation in vitro (IC50 = 2.84 μM).



Product References
1. Selwood et al (2001)  J.Med.Chem. 44 78.
2. Evgenov et al (2006) l. Nat.Rev.Drug Discov. 5 755.