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Phorbol 12,13-dibutyrate (CAS 75567-37-2)




Product specification

Formula: C28H40O8
MW: 504.61
Purity: >98%
Appearance: White lyophilised solid
Solubility: 50 mM in DMSO
Storage: -20°C.
CAS Number: 37558-16-0
Synonyms: Phorbol 12,13-dibutyrate
Cat.number: VD-ESA-0024

Product Description

Phorbol 12,13-dibutyrate (CAS 37558-16-0) is a protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca2+ concentration. Also inhibits the activity of Na+,K+ ATPase in OK cells.



Product References
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2. Hori et al (1999)  J.Neurosci. 19 7262.
3. Sakai et al (2010) J.Smooth Muscle Res. 46 259.