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VD-PI-0093-0001-1g 30 USD
VD-PI-0093-0010-10g 280 USD

Clofibrate




Product specification

Formula: C12H15ClO3
MW: 242.70
Purity: >=99% by HPLC
Appearance: Colorless oil
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
CAS Number: 637-07-0
Synonyms: Chemical Name: Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
Cat.number: VD-PI-0093

Product Description

The peroxisome-proliferating receptors PPAR agonist (EC50 values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.



Product References
Merck Index 12 2437. Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34. Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823. Willson et al (2000) The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 43 527.