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SOTS-1 (CAS 223507-96-8)




Product specification

Formula: C16H14N2O6
MW: 330.3
Purity: >80%
Appearance: Crystalline solid
Solubility: 10 mg/ml in DMSO; ~2 mg/ml in DMF
Storage: -80°C
CAS Number: 223507-96-8
Synonyms: Di-(4-Carboxybenzyl)Hyponitrite,
Superoxide Thermal Source
Cat.number: VD-NP-0003

Product Description

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 (CAS 223507-96-8) is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature.1,2 This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo.



Product References
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