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Acyclovir (CAS 59277-89-3)




Product specification

Formula: C8H11N5O3
MW: 225.21
Purity: >=99% by (HPLC)
Appearance: White crystalline solid
Solubility: 50 mM in 1eq. HCl and to 20 mM in DMSO
Storage: RT
CAS Number: 59277-89-3
Synonyms: Acycloguanosine, NSC 645011
Cat.number: VD-HV-0098

Product Description

Acyclovir (CAS 59277-89-3) is an antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC50 values are 0.85 and 0.86 μM respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).



Product References
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2. Hayashi et al (2006) J.Gene.Med. 8 1056.
3. Suzuki et al (2006) Antiviral Res. 72 157.