| Product # | Price | Quantity | Add to cart |
| VD-TMR-0007-0025-25mg | 110 USD | ||
| VD-TMR-0007-0100-100mg | 350 USD |
DC 260126 (CAS 346692-04-4)
Product specification
| Formula: | C16H18FNO2S |
| MW: | 307.38 |
| Purity: | >98% |
| Appearance: | White solid. |
| Solubility: | 100 mM in DMSO and to 100 mM in ethanol |
| Storage: | -20°C. |
| CAS Number: | 346692-04-4 |
| Synonyms: | DC260126 |
| Cat.number: | VD-TMR-0007 |
Product Description
DC 260126 (CAS 346692-04-4) is a free fatty acid receptor 1 (FFA1/GPR40) antagonist. Inhibits FFA-induced increases in intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. Decreases serum insulin levels, improves insulin sensitivity and reduces the number of apoptotic pancreatic β cells in obese diabetic (db/db) rats.
Product References
1. Hu et al (2009) Biochem.Biophys.Res.Comm. 390 557.
2. Zhang et al (2010) Biomed.Pharmacother. 64 647.
3. Sun et al (2013) PLoS ONE 8 e66744.
2. Zhang et al (2010) Biomed.Pharmacother. 64 647.
3. Sun et al (2013) PLoS ONE 8 e66744.