| Product # | Price | Quantity | Add to cart |
| VD-TMR-0008-0010-10mg | 90 USD | ||
| VD-TMR-0008-0050-50mg | 340 USD |
Eplivanserin hemifumarate (CAS 130580-02-8)
Product specification
| Formula: | C19H21FN2O2.0.5C4H4O4 |
| MW: | 386.42 |
| Purity: | >98% |
| Appearance: | White crystalline solid |
| Solubility: | 50 mM in DMSO |
| Storage: | +4˚C. |
| CAS Number: | 130580-02-8 |
| Synonyms: | SR-46349 hemifumarate, SR-46349B |
| Cat.number: | VD-TMR-0008 |
Product Description
Eplivanserin hemifumarate (CAS 130580-02-8) is a potent and selective 5-HT2A antagonist (IC50 values are 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively). Attenuates cocaine-induced hyperactivity. Increases dopamine (DA) release in rat medial prefrontal cortex (mPFC); potentiates haloperidol-induced DA release in the mPFC and nucleus accumbens.
Product References
1. Bonaccorso et al (2002) 27 430.
2. Filip et al (2004) J.Pharmacol.Exp.Ther. 310 1246.
3. Yadav et al (2011) J.Pharmacol.Exp.Ther. 339 99.
2. Filip et al (2004) J.Pharmacol.Exp.Ther. 310 1246.
3. Yadav et al (2011) J.Pharmacol.Exp.Ther. 339 99.