| Product # | Price | Quantity | Add to cart |
| VD-TMR-0012-0010-10mg | 99 USD | ||
| VD-TMR-0012-0050-50mg | 440 USD |
MK 0677 (CAS 159752-10-0)
Product specification
| Formula: | C27H36N4O5S.CH3SO3H |
| MW: | 624.77 |
| Purity: | >98% |
| Appearance: | Off-white solid. |
| Solubility: | 50 mM in water and to 100 mM in DMSO |
| Storage: | +4˚C. |
| CAS Number: | 159752-10-0 |
| Synonyms: | Ibutamoren mesylate, L-163,191 |
| Cat.number: | VD-TMR-0012 |
Product Description
MK 0677 (CAS 159752-10-0) is a high affinity ghrelin receptor agonist (pKi = 8.14). Growth hormone (GH) secretagog; stimulates GH release from rat pituitary cells in vitro (EC50 = 1.3 nM) and enhances GH plasma levels in vivo. Also attenuates isoproterenol-induced lipolysis in rat adipocytes in vitro. Orally bioavailable.
Product References
1. Patchett et al (1995) Proc.Natl.Acad.Sci.U.S.A. 92 7001.
2. Mucciolo et al (2004) Eur.J.Pharmacol. 498 27.
3. Bennett et al (2009) Mol.Pharmacol. 76 802.
2. Mucciolo et al (2004) Eur.J.Pharmacol. 498 27.
3. Bennett et al (2009) Mol.Pharmacol. 76 802.