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VD-AM-0111-0100-100mg 70 USD
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(±)-Thalidomide (CAS 50-35-1)

Product specification

Formula:  C13H10N2O4
MW: 258.2
Purity: ≥98% by TLC
Appearance: White solid
Solubility: DMSO
Storage: +15°C to +30°C
CAS Number: 50-35-1
Synonyms: (±)-2-(2,6-Dioxo-3-piperidinyl)-
Cat.number: VD-AM-0111

Product Description

(±)-Thalidomide (CAS 50-35-1) is a selective inhibitor of tumor necrosis factor alpha (TNF-α) biosynthesis. Blocks basic fibroblast growth factor (bFGF)-induced angiogenesis in cornea. An immunomodulator that inhibits replication of the HIV-1 virus. Has been used to treat AIDS-related oral ulcers. Teratogen, sedative-hypnotic with inherent anti-inflammatory properties, anticoagulant.

Product References
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2. Thompson, C. 1995. Lancet 346, 1289.
3. Tramontana, J.M., et al. 1995. Mol. Med. 1, 384.
4. D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 4082.