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VD-Ant-0257-0010-10mg 80 USD
VD-Ant-0257-0100-100mg 700 USD

Bumetanide (CAS 28395-03-1)




Product specification

Formula: C17H20N2O5S
MW: 364.42
Purity: >99 %
Appearance: White Solid
Solubility: Acetone, Benzene, Ethanol, Methanol, Propylene Glycol
Storage: 4˚C
CAS Number: 28395-03-1
Synonyms: Bufenox; Bumex; Burinex; Fordiuran;
Lixil; Lunetoron; PF 1593; Ro 10-6338;
Cat.number: VD-Ant-0257

Product Description

Loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide.



Product References
O'Grady et al (1987) Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am.J.Physiol. 253 C177. Isenring and Forbush (1997) Ion and bumetanide binding by the Na-K-Cl cotransporter. J.Biol.Chem. 272 24556. Morita et al (1999) Functional evidence for involvement of bumetanide-sensitive Na+K+2Cl- cotransport in the hepatoportal Na+ receptor of the sprague-dawley rat. Neurosci.Letts. 264 65.