Product # Price Quantity Add to cart
VD-NP-0002-0010-10 mg 120 USD
VD-NP-0002-0100-100 mg 1050 USD


Product specification

Formula: C14H11F5N2O2S
MW: 366.3
Purity: ≥90% by HPLC.
Appearance: Yellow solid.
Solubility: DMSO or MeOH.
Storage: +2°C to +8°C.
CAS Number: 195533-44-9
Synonyms: T1, (4-N,N′-Dimethylanilino)-pentafluorosulfonamide
Cat.number: VD-NP-0002

Product Description

A cell-permeable pentafluorosulfonamide compound that induces microtubule depolymerization and cell-cycle arrest by irreversibly modifying β-tubulin. T113242-induced activation of gene transcriptions has been shown to be mediated by Erk signalling pathway and the transcription factor MIZ-1 (myc-interacting zinc finger protein). 

Product References

Ziegelbauer, J., et al. 2004. Proc. Natl. Acad. Sci. USA 101, 458. Ziegelbauer, J., et al. 2001. Mol. Cell 8, 339