Product # Price Quantity Add to cart
VD-ACR-0005-0010-10mg 100 USD
VD-ACR-0005-0050-50 mg 400 USD


Product specification

Formula: C22H16ClN3O2
MW: 389.8
Purity: ≥98%
Appearance: Off-white solid.
Solubility: DMSO
Storage: -20°C. Protect from light.
CAS Number: 204205-90-3
Synonyms: N-(Pyridin-4-yl)-[1-(4-chlorobenzyl)-indol-3-yl]-glyoxyl Amide
Cat.number: VD-ACR-0005

Product Description

A cell-permeable, potent anticancer agent that destabilizes microtubules in tumor cells as well as in a cell-free system. Binds directly to tubulin and inhibits polymerization (IC50 = 300 nM). Also blocks cell cycle at G2/M phase, shows efficacy toward multidrug-resistant (MDR) tumor cells, and shows no neurotoxicity.

Product References

1.Bacher, G., et al. 2001. Cancer Res. 61, 392.