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VD-NP-0005-0010-10mg 80 USD
VD-NP-0005-0100-100mg 500 USD

M50054




Product specification

Formula: C13H16O4
MW: 236.26
Purity: ≥95%
Appearance: White to off-white solid.
Solubility: DMSO or EtOH
Storage: +2°C to +8°C. Protect from light.
CAS Number: 54135-60-3
Synonyms: 2,2'-methylenebis(cyclohexane-1,3-dione)
Cat.number: VD-NP-0005

Product Description

A cell-permeable inhibitor of apoptosis induction (IC50 = 67 µg/ml in FasL-stimulated WC8 cells, 130 µg/ml in etoposide-stimulated U937 cells). Effects attributable to the inhibition of caspase-3 activation but does not directly inhibit caspase-3 even at 1 mg/ml.



Product References
1.Tsuda, T., et al. 2001. Eur. J. Pharmacol. 433, 37.