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PRIMA-1 (CAS 5608-24-2)




Product specification

Formula: C9H15NO3
MW: 185.2
Purity: ≥95% by NMR.
Appearance: Off-white solid.
Solubility: H2O.
Storage: +2°C to +8°C. Protect from light.
CAS Number: 5608-24-2
Synonyms: 2,2-bis(hydroxymethyl)quinuclidin-3-one
Cat.number: VD-NP-0009

Product Description

A cell-permeable quinuclidinone analog with antitumor properties. Restores biochemical and biological function to mutant p53 and induces p53-dependent apoptosis in vitro and in vivo. Induces apoptosis in breast cancer cells expressing mutant p53.



Product References
1.Bykov, V.J., et al. 2002. Nat. Med. 8, 282.