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MDM2 Inhibitor (CAS 562823-84-1)




Product specification

Formula: C15H12BIO3
MW: 377.97
Purity: >=95%.
Appearance: Pale yellow solid.
Solubility: DMSO.
Storage: +2°C to +8°C.
CAS Number: 562823-84-1
Synonyms: (E)-4-(3-(4-iodophenyl)acryloyl)phenylboronic acid
Cat.number: VD-NP-0011

Product Description

A cell-permeable boranyl-chalcone that binds strongly to MDM2 and irreversibly disrupts MDM2/p53 protein complex. Exhibits selective toxicity towards MDM2 overexpressing human breast cancer cell lines.



Product References
1.Kumar, S.K., et al. 2003. J. Med. Chem. 46, 2813.