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VD-NP-0013-0025-25mg 60 USD
VD-NP-0013-0100-100mg 200 USD

Inhibitor of Trichostatin A 1

Product specification

Formula: C13H7Cl2N3O
MW: 292.1
Purity: ≥95% by HPLC
Appearance: White solid
Solubility: DMSO
Storage: +2°C to +8°C. Protect from light. Packaged under inert gas.
CAS Number: 200626-61-5
Synonyms: ITSA1;N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide
Chemical name:(1H-benzo[d][1,2,3]triazol-1-yl)(2,4-dichloro-phenyl)methanone
Cat.number: VD-NP-0013

Product Description

A cell-permeable benzotriazole amide that counteracts and complements histone and tubulin deacetylase (HDAC and TDAC) inhibitors. Inhibits tubulin acetylation mediated by Trichostatin A, but not by Taxol. Through its successful use with TSA in vivo, it was shown that the expression of Rhodopsin-GFP transgene in Zebrafish eye is regulated via a mechanism involving reversible histone acetylation.

Product References
Haggarty, S.J., et al. 2003. Chem. Biol. 10, 383. Koeller, K.M., et al. 2003. Chem. Biol. 10, 397.