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VD-NP-0016-0050-50mg 55 USD
VD-NP-0016-0100-100mg 90 USD

ACA




Product specification

Formula: C21H23NO3
MW: 337.4
Purity: ≥99% by TLC
Appearance: White solid
Solubility: DMSO or EtOH
Storage: +15°C to +30°C.
CAS Number: 110683-10-8
Synonyms: N-(p-Amylcinnamoyl)anthranilic acid
Cat.number: VD-NP-0016

Product Description

A cell-permeable inhibitor of phospholipase A2 that blocks epinephrine-stimulated thromboxane production in platelets. Inhibits ATP-stimulated phosphatidylcholine (PC) secretion in alveolar type II cells. Also blocks phorbol ester and A23187-induced PC secretion in type II cells. Reported to block glucose-induced insulin secretion by pancreatic β-cells. Exhibits moderate leukotriene antagonist activity.



Product References
1.Liu, L., et al. 1999. J. Cell. Biochem. 72, 103.
2.Simonsson, E., et al. 1998. Diabetes 47, 1436.
3.Konrad, R.J., et al. 1992. Biochim. Biophys. Acta 1135, 215.