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VD-NP-0028-0005-1mg 75 USD
VD-NP-0028-0010-10mg 550 USD

CA 074

Product specification

Formula: C18H29N3O6
MW: 383.4
Purity: >=98%
Appearance: Colorless or white solid.
Solubility: DMSO.
Storage: -20°C.Protect from light.
CAS Number: 134448-10-5
Synonyms: Cathepsin B Inhibitor III
Cat.number: VD-NP-0028

Product Description

An epoxysuccinyl peptide that acts as a potent, irreversible, and specific inhibitor of cathepsin B (IC50 = 2.24 nM for rat liver cathepsin B). Reduces ischemia-induced neuronal death. Exhibits lower membrane permeability when compared to CA-074 Me.  

Product References
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4.Inubushi, T., et al. 1994. J. Biochem. 116, 282.
5.Murata, M., et al. 1991. FEBS Lett. 280, 307.