Product # Price Quantity Add to cart
VD-CHR-0002-0005-5mg 400 USD
VD-CHR-0002-0050-50mg 3250 USD

A-85380 dihydrochloride

Product specification

Formula: C9H14Cl2N2O
MW: 237.13
Purity: ≥95%
Appearance: Off-white solid
Solubility: H2O:10 mg/mL
Storage: Hygroscopic
CAS Number: Not available
Synonyms: 3-((2S)-Azetidinylmethoxy)pyridinedihydrochloride
Cat.number: VD-CHR-0002

Product Description

A potent and selective neuronal nicotinic acetylcholine receptor (nAChR) agonist. The 5125I-analog has been used as a selective radioligand for the α4β2 nAChR subtype. Fluorinated analogs have been used for PET imaging of nAChRs.

Product References
1. Abreo, M.A., et al. 1996. J. Med. Chem. 39: 817-825.
2. Mukhin, A.G., et al. 2000. Mol. Pharmacol. 57: 642-649.
3. Horti, A.G., et al. 1998. Nucl. Med. Biol. 25: 599-603.