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VD-IS-0044-0010-10mg 70 USD
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AG 18 (CAS 118409-57-7)




Product specification

Formula: C10H6N2O2
MW: 186.17
Purity: ≥98% by HPLC
Appearance: Yellow solid
Solubility: 20 mM in EtOH, to 100 mM in DMSO or Acetic acid.
Storage: -20°C. Protect from light.
CAS Number: 118409-57-7
Synonyms: RG-50810; Tyrphostin A 23
Cat.number: VD-IS-0044

Product Description

AG 18 (CAS 118409-57-7) is an inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling. 



Product References
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