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VD-NP-0117-0001-1mg 150 USD
VD-NP-0117-0010-10mg 1300 USD

Zinbo-5




Product specification

Formula: C22H21N3O4
MW: 391.4
Purity: ≥98%
Appearance: Liquid
Solubility: DMSO
Storage: -20°C
CAS Number: Not available.
Synonyms: 2-(4,5-Dimethoxy-2-hydroxyphenyl)-4-
(2-pyridylmethyl)aminomethylbenzoxazole
Cat.number: VD-NP-0117

Product Description

Zinbo-5 is a cell-permeable benzoxazole containing tetradentate fluorescent sensor that serves as a selective and sensitive ratiometric imaging probe for Zn2+ and Cd2+ (by fluorescence I445 nm/I400 nm or by absorbance I376 nm/I337 nm). Forms a 1:1 complex with zinc (Kd = 2.2 nM, pH 7.2) and displays characteristic changes in both excitation and emission spectra with ~5-fold increase in fluorescence quantum yield. Shown to reveal changes in intracellular zinc availability in mouse fibroblasts L(TK-) cells by two-photon excitation fluorescence microscopy and useful for real time monitoring of Zn2+ in tissues and cells.



Product References
1. Taki, M., et al. 2004. J. Am. Chem. Soc. 126, 712.