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PRIMA-1MET (CAS 5291-32-7)




Product specification

Formula: C10H17NO3
MW: 199.25
Purity: >=98%
Appearance: White solid.
Solubility: DMSO and Water.
Storage: +4°C
CAS Number: 5291-32-7
Synonyms: 2-(hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one
Cat.number: VD-NP-1004

Product Description

PRIMA-1MET (CAS 5291-32-7) is a methylated derivative of PRIMA-1. Restores mutant activity p53 activity. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation.



Product References
1. Bykov et al (2005) PRIMA-1MET synergizes with cisplatin to induce tumor cell apoptosis. Oncogene 24 3484.