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LY 294002 (CAS 154447-36-6)




Product specification

Formula: C19H17NO3.HCl
MW: 343.81
Purity: >=98%
Appearance: White crystalline solid.
Solubility: DMSO to 25 mM.
Storage: RT. Keep cool and dry.
CAS Number: 154447-36-6
Synonyms: 2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride
Cat.number: VD-CCR-0117

Product Description

LY 294002 (CAS 154447-36-6) is a highly selective inhibitor of phosphatidylinositol 3-kinase (IC50 values are 0.31, 0.73, 1.06 and 6.60 μM for PI3Kβ, PI3Kα, PI3Kδ and PI3Kγ respectively). Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo.



Product References
1.Vlahos et al (1994. J.Biol.Chem. 269 5241.
2.Chasserot-Golaz et al (1998). J.Neurochem. 70 2347.