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VD-NP-1005-0010-10mg 100 USD
VD-NP-1005-0050-50mg 450 USD

CYM 5442 hydrochloride

Product specification

Formula: C23H27N3O4 • HCl • xH2O
MW: 445.94 (anhydrous)
Purity: >=99%
Appearance: Off-white solid.
Solubility: Water to 10 mM or DMSO to 100 mM.
Storage: -20°C.Protect from light.
CAS Number: 1094042-01-9
Synonyms: Not available.
Cat.number: VD-NP-1005

Product Description

CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent.

Product References

1. Gonzalez-Cabrera, P.J., et al. 2008. Mol. Pharmacol. 74: 1308-1318.