4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide

$150.00$1,250.00

Product Specification

  • Appearance
    :

    Crystalline solid

  • CAS Number
    :

    N/A

  • Cat.number
    :

    VD-OEIA-00101

  • Formula
    :

    C15H23N3O3

  • MW
    :

    293.4

  • Purity
    :

    ≥98%

  • Solubility
    :

    N/A

  • Storage
    :

    N/A

  • Synonyms
    :

    N/A

  • Size
    :

    100mg, 10mg

Product Variations

Product # Price Quantity  
VD-OEIA-00101-0010-10mg $150
VD-OEIA-00101-0100-100mg $1250

Description

Histone deacetylase (HDAC1) inhibitor. Similar potency is displayed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. Thus compound is a selective and cost-effective for the inhibition of HDAC.

1.Jung, M., Hoffmann, K., Brosch, G., et al. Bioorg Medicinal Chem Letters 7 1655-1658 (1997).
2.Taunton, J., Hassig, C.A., Schreiber, S.L. Science 272 408-411 (1996).

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