CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0096-0010-10mg | $90 | ||
| VD-PI-0096-0050-50mg | $450 |
AM 80
$90.00 – $450.00
Product Specification
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Appearance:
White Solid
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CAS Number:
94497-51-5
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Cat.number:
VD-PI-0096
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Formula:
C22H25NO3
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MW:
351.44
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Purity:
>=99%
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Solubility:
100 mM in 1.1eq. NaOH and to 50 mM in DMSO.
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Storage:
Store at RT
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Synonyms:
Tamibarotene
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Size:
10mg, 50mg
Description
Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
1.Kagechika et al (1988),J.Med.Chem. 31 218
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