Casein Kinase II Inhibitor III

$95.00$900.00

Product Specification

  • Appearance
    :

    Off-white solid

  • CAS Number
    :

    934358-00-6

  • Cat.number
    :

    VD-OEIA-0023

  • Formula
    :

    C9H4Br4O2

  • MW
    :

    463.8

  • Purity
    :

    >=95%

  • Solubility
    :

    DMSO or EtOH.

  • Storage
    :

    -20°C.Protect from light.

  • Synonyms
    :

    CKII Inhibitor, TBCA

  • Size
    :

    50mg, 5mg

Product Variations

Product # Price Quantity  
VD-OEIA-0023-0005-5mg $95
VD-OEIA-0023-0050-50mg $900

Description

A cell-permeable tetrabrominated cinnamic acid compound that acts as a potent and ATP-competitive inhibitor of Casein Kinase II (IC50 = 110 nM, Ki = 77 nM) with greater selectivity than TBB and DMAT against a panel of 28 commonly studied kinases. Shown to efficiently induces apoptosis in Jurkat cells (DC50 = 7.7 µM).

1.Pagano, M.A., et al. 2006. Chembiochem 8, 129.

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