DGAT-1 Inhibitor

$200.00$750.00

Product Specification

  • Appearance
    :

    Pale yellow solid.

  • CAS Number
    :

    959122-11-3

  • Cat.number
    :

    VD-OEIA-1063

  • Formula
    :

    C25H24N2O4

  • MW
    :

    428.48

  • Purity
    :

    >=98%

  • Solubility
    :

    50 mM in DMSO.

  • Storage
    :

    +2°C to +8°C.

  • Synonyms
    :

    A 922500

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-1063-0010-10mg $200
VD-OEIA-1063-0050-50mg $750

Description

Diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively) that is devoid of activity at DGAT-2, ACAT1 or ACAT2. Induces significant weight loss without altering food intake, and decreases liver and plasma triglyceride levels in vivo. Orally active.

1.Zhao et al (2008). J.Med.Chem. 51 380.

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