FBPase-1 Inhibitor

$80.00$300.00

Product Specification

  • Appearance
    :

    Off-white solid

  • CAS Number
    :

    883973-99-7

  • Cat.number
    :

    VD-OEIA-10014

  • Formula
    :

    C13H7Cl3N2O3S

  • MW
    :

    377.6

  • Purity
    :

    ≥97%

  • Solubility
    :

    DMSO

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    F16BPase Inhibitor

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-10014-0010-10mg $80
VD-OEIA-10014-0050-50mg $300

Description

A cell-permeable benzoxazolo-sulfonamide compound that inhibits hFBPase-1 (human fructose-1,6-bisphosphatase) enzymatic activity (IC50=3.4 µM) by competing at the AMP allosteric binding site. Shown to block glucose production in starved rat hepatoma cells (IC50=6.6 µM).

1.Lai, C., et al. 2006. Bioorg. Med. Chem. Lett. 16, 1807.

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