Histone Deacetylase Inhibitor III

$45.00$320.00

Product Specification

  • Appearance
    :

    White Solid

  • CAS Number
    :

    251456-60-7

  • Cat.number
    :

    VD-OEIA-0026

  • Formula
    :

    C16H25N3O3

  • MW
    :

    307.39

  • Purity
    :

    ≥98%

  • Solubility
    :

    100 mM in DMSO and to 20 mM in EtOH.

  • Storage
    :

    -20°C. Protect from light.

  • Synonyms
    :

    M 344; 4-Dimethylamino-N-(6-hydroxycarbamoylhexyl) benzamide

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-0026-0010-10mg $45
VD-OEIA-0026-0050-50mg $320

Description

A cell-permeable amide analog of Trichostatin A that potently inhibits histone deacetylases (IC50 = 40 nM for rat liver HDAC and IC50=100 nM for maize HD).Induces differentiation and inhibits proliferation (~2 μM) of murine erythroleukemia cells.

1.Ramiszewski, S.W., et al. 2002. J. Med. Chem. 45, 753.
2.Jung, M., et al. 1999. J. Med. Chem. 42, 4669.

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