kb NB 142-70 (CAS 1233533-04-4)

$120.00$550.00

Product Specification

  • Appearance
    :

    Off-white solid

  • CAS Number
    :

    1233533-04-4

  • Cat.number
    :

    VD-OEIA-1007

  • Formula
    :

    C11H9NO2S2

  • MW
    :

    251,32

  • Purity
    :

    >=98%

  • Solubility
    :

    100 mM in DMSO.

  • Storage
    :

    RT. Protect from light.

  • Synonyms
    :

    9-hydroxy-3,4-dihydrobenzo[4,5]- thieno[2,3-f][1,4]thiazepin-5(2H)-one

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-1007-0010-10mg $120
VD-OEIA-1007-0050-50mg $550

Description

Selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). More potent analog of CID 755673 with 7-fold greater inhibition. Inhibits prostrate cancer cell migration and invasion and reduces wound healing in vitro; displays prominent cytotoxic and anti-proliferative effects.

1.Bravo-Altamirano et al., ACS Med.Chem.Lett. 2 154, (2011).
2.LaValle et al., BMC Chemical Biology 10 5, (2010).

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