CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-1083-0010-10mg | $120 | ||
| VD-OEIA-1083-0050-50mg | $550 |
L 006235
$120.00 – $550.00
Product Specification
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Appearance:
White solid.
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CAS Number:
294623-49-7
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Cat.number:
VD-OEIA-1083
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Formula:
C24H30N6O2S
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MW:
466.6
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Purity:
>=98%
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Solubility:
DMSO to 100 mM.
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
N/A
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Size:
10mg, 50mg
Description
Potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S. Displays reduced selectivity in cell-based assays possibly due to lysosomal accumulation. Reduces collagen breakdown and promotes bone deposition in vivo. Orally active and has intrinsic fluorescence.
1.Falgueyret et al (2005). J.Med.Chem. 48 7535.
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