MI 2 (MALT1 inhibitor)

$150.00$600.00

Product Specification

  • Appearance
    :

    White solid.

  • CAS Number
    :

    1047953-91-2

  • Cat.number
    :

    VD-OEIA-0152

  • Formula
    :

    C19H17Cl3N4O3

  • MW
    :

    455.72

  • Purity
    :

    >=98%.

  • Solubility
    :

    100 mM in DMSO and to 50 mM in Ethanol.

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    MALT1 inhibitor

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-0152-0010-10mg $150
VD-OEIA-0152-0050-50mg $600

Description

MALT1 inhibitor.Binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF-κB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo.
1.Fontan et al (2012); Cancer Cell 22 812.

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