CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0177-0005-5mg | $170 | ||
| VD-PI-0177-0050-50mg | $1450 |
PD 151746
$170.00 – $1,450.00
Product Specification
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Appearance:
Orange solid
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CAS Number:
179461-52-0
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Cat.number:
VD-PI-0177
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Formula:
C11H8FNO2
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MW:
237.3
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Purity:
>=95%
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Solubility:
DMSO or MeOH
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Storage:
-20°C.Protect from light.
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Synonyms:
3-(5-Fluoro-3-indolyl)-2-mercapto-(Z)-2-propenoic Acid
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Size:
50mg, 5mg
Description
A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the calcium binding sites of calpain. Displays over 20-fold greater selectivity for calpain-1 over calpain-2 (Ki values: 260 nM and 5.33 µM, respectively). Has been shown to prevent cycloheximide-induced apoptosis.
1.Squier, M.K., et al. 1999. J. Cell Physiol. 178, 311.
2.Wang, K.K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 6687.
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