PMX 464

$100.00$400.00

Product Specification

  • Appearance
    :

    Beige solid.

  • CAS Number
    :

    485842-97-5

  • Cat.number
    :

    VD-OEIA-0127

  • Formula
    :

    C13H9NO2S

  • MW
    :

    243.28

  • Purity
    :

    >=98%.

  • Solubility
    :

    100 mM in DMSO and to 100 mM in Ethanol.

  • Storage
    :

    -20°C.Protect from light.

  • Synonyms
    :

    N/A

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-0127-0010-10mg $100
VD-OEIA-0127-0050-50mg $400

Description

Putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system. Shown to inhibit Trx and induce a G1/S block in HT29 cells; inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Also elicits an anti-inflammatory response in A549 cells.

1.Mukherjee et al (2005); Br.J.Cancer 92 350.
2.Callister et al (2008); Br.J.Pharmacol. 155 661.

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