CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0059-0010-10mg | $100 | ||
| VD-OEIA-0059-0050-50mg | $450 |
SANT-1 (CAS 304909-07-7)
$100.00 – $450.00
Product Specification
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Appearance:
Pale yellow solid
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CAS Number:
304909-07-7
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Cat.number:
VD-OEIA-0059
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Formula:
C23H27N5
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MW:
373.49
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Purity:
>=99% by (HPLC)
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Solubility:
25 mM in Ethanol and to 50 mM in DMSO.
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Storage:
-20°C.Protect from light.
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Synonyms:
N/A
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Size:
10mg, 50mg
Description
SANT-1 (CAS 304909-07-7) is a potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM). Inhibits smoothened agonist effects with an IC50 of 20 nM (in Shh-LIGHT2 cells).
1.Chen et al (2002) Small molecule modulation of smoothened activity. Proc.Natl.Acad.Sci.USA. 99 14071.
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