CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-1069-0010-10mg | $150 | ||
| VD-OEIA-1069-0050-50mg | $500 |
SB 431542
$150.00 – $500.00
Product Specification
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Appearance:
Yellow solid.
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CAS Number:
301836-41-9
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Cat.number:
VD-OEIA-1069
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Formula:
C22H16N4O3
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MW:
384.39
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Purity:
>=98%
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Solubility:
10 mM in Ethanol and to 100 mM in DMSO.
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Storage:
RT. Keep cool and dry.
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Synonyms:
N/A
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Size:
10mg, 50mg
Description
Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells.
1.Inman et al (2002). Mol.Pharmacol. 62 65.
2.Laping et al (2002). Mol.Pharmacol. 62 58.
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