Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-OEIA-10004-0005-5mg | $100 | ||
VD-OEIA-10004-0025-25mg | $350 |
$100.00 – $350.00
Clear oil
915754-88-0
VD-OEIA-10004
C19H26N2O4S2
410.6
≥95%
DMSO
+2°C to +8°C. Protect from light.
Secreted Frizzled Related Protein-1 Inhibitor
25mg, 5mg
Product # | Price | Quantity | |
---|---|---|---|
VD-OEIA-10004-0005-5mg | $100 | ||
VD-OEIA-10004-0025-25mg | $350 |
A diphenylsulfone-sulfonamide compound that counteracts the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and Wnt-3/frizzled-stimulated cellular functions (EC50=1.27 µM in a U2OS-based reporter assay) with a reported aqueous solubility of 26 µg/ml at pH 7.4 and in vitro half-lives of 12 and 26.7 min using rat and human microsomes, respectively.
1.Gopalsamy, A., et al. 2008. J. Med. Chem. 51, 7670.
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