CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0003-0001-1mg | $40 | ||
| VD-PI-0003-0005-5mg | $150 |
SJA 6017
$40.00 – $150.00
Product Specification
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Appearance:
White lyophilized solid
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CAS Number:
190274-53-4
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Cat.number:
VD-PI-0003
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Formula:
17H25FN2O4S
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MW:
372.5
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Purity:
≥95% by HPLC
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Solubility:
DMSO
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Storage:
PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS
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Synonyms:
N-(4-Fluorophenylsulfonyl)-L-valyl-L-leucin
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Size:
1mg, 5mg
Description
A potent, cell-permeable, reversible inhibitor of calpain (IC50= 7.5 nM for calpain and 78 nM for m-calpain). Also potently inhibits cathepsin B(IC50 = 15 nM) and L (IC50 = 1.6 nM). Reduces bFGF-induced angiogenesis in rat cornea and prevents selenite cataract formation. Reduces A23187-induced nuclear opacity and proteolysis of crystallins and -spectrin in cultured lenses.
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