Smad3 Inhibitor; SIS3 (CAS 1009104-85-1)

$95.00$700.00

Product Specification

  • Appearance
    :

    Off-white solid

  • CAS Number
    :

    1009104-85-1

  • Cat.number
    :

    VD-OEIA-00106

  • Formula
    :

    C28H27N3O3

  • MW
    :

    453.5

  • Purity
    :

    >=98%.

  • Solubility
    :

    DMSO or EtOH.

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    Specific Inhibitor of Smad3, SIS3

  • Size
    :

    10mg, 1mg

Product Variations

Product # Price Quantity  
VD-OEIA-00106-0001-1mg $95
VD-OEIA-00106-0010-10mg $700

Description

Smad3 inhibitor; SIS3 (CAS 1009104-85-1) is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling with no effect on Smad2, p38 MAPK, ERK, or PI 3-K signaling.

1.Jinnin, M., et al. 2006. Mol. Pharmacol. 69, 597.

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