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DNA-PK Inhibitor (CAS 20357-25-9)




Product specification

Formula: C₉H₉NO₅
MW: 211.2
Purity: ≥90% by GC.
Appearance: Bright yellow solid.
Solubility: DMSO.
Storage: +2°C to +8°C.
CAS Number: 20357-25-9
Synonyms: DMNB; 4,5-Dimethoxy-2-nitrobenzaldehyde
Cat.number: VD-DDR-2001

Product Description

DNA-PK Inhibitor (CAS 20357-25-9) is a cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-PK (DNA-dependent protein kinase) activity (IC50 = 15 µM) and DNA-PK-mediated DSB (double strand break) DNA repair by NHEJ (non-homologous DNA-end-joining).



Product References
1.Willmore, E., et al. 2004. Blood,103, 4659.
2.Durant, S., and Karran, P. 2003. Nucleic Acids Res. 31, 5501.