Product # Price Quantity Add to cart
VD-AM-0105-0010-10mg 60 USD
VD-AM-0105-0050-50mg 255 USD

Tranilast (CAS 53902-12-8)




Product specification

Formula: C18H17NO5
MW: 327.34
Purity: ≥98% (HPLC)
Appearance: Off-white solid
Solubility: 100 mM in DMSO
Storage: 2-8°C
CAS Number: 53902-12-8
Synonyms: Rizaben;
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-
2-propenyl]amino]benzoic acid
Cat.number: VD-AM-0105

Product Description

Tranilast (CAS 53902-12-8) is an anti-allergic via inhibition of chemical mediator release from mast cells. Most recently shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor. 



Product References
1. Miyazawa et al (1996) Br.J.Pharmacol. 118 915.
2. Hishikawa et al (1996) J.Cardiovasc.Pharmacol. 28 200.
3. Isaji et al (1997) Br.J.Pharmacol. 122 1061.
4. Jin et al (1998) 361 199.