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VD-IV-0111-0100-100mg 70 USD
VD-IV-0111-0500-500mg 325 USD

Thalidomide (CAS 50-35-1)




Product specification

Formula: C13H10N2O4
MW: 258.2
Purity: ≥98% by TLC
Appearance: White solid
Solubility: DMSO
Storage:
CAS Number: 50-35-1
Synonyms: (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-
isoindole-1,3(2H)-dione
Cat.number: VD-IV-0111

Product Description

Thalidomide (CAS 50-35-1) is a selective inhibitor of TNFbiosynthesis. Blocks basic fibroblast growth factor (bFGF)-induced angiogenesis in cornea. An immunomodulator that inhibits replication of the HIV-1 virus. Has been used to treat AIDS-related oral ulcers.



Product References
Gershon, D. 1995. Nat. Med. 1, 1230.
Thompson, C. 1995. Lancet 346, 1289.
Tramontana, J.M., et al. 1995. Mol. Med. 1, 384.
D’Amato, R.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 4082.