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VD-PI-0018-0005-5mg 100 USD
VD-PI-0018-0050-50mg 800 USD

Prolyl Endopeptidase Inhibitor II




Product specification

Formula: C18H22N2O4
MW: 330.4
Purity: ≥90% by HPLC
Appearance: Off-white oil
Solubility: DMSO, DMF, or EtOAc
Storage: PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS
CAS Number: 86925-97-5
Synonyms: Z-PP-CHO
Cat.number: VD-PI-0018

Product Description

A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow, and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain, respectively). Reported to form a hemiacetal with the active site serine of the enzyme.



Product References