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VD-OEIA-0023-0005-5mg 95 USD
VD-OEIA-0023-0050-50mg 900 USD

Casein Kinase II Inhibitor III




Product specification

Formula:  C9H4Br4O2
MW: 463.8
Purity: >=95%
Appearance: Off-white solid.
Solubility: DMSO or EtOH.
Storage: -20°C.Protect from light.
CAS Number: 934358-00-6
Synonyms: CKII Inhibitor, TBCA
Cat.number: VD-OEIA-0023

Product Description

A cell-permeable tetrabrominated cinnamic acid compound that acts as a potent and ATP-competitive inhibitor of Casein Kinase II (IC50 = 110 nM, Ki = 77 nM) with greater selectivity than TBB and DMAT against a panel of 28 commonly studied kinases. Shown to efficiently induces apoptosis in Jurkat cells (DC50 = 7.7 µM).



Product References
1.Pagano, M.A., et al. 2006. Chembiochem 8, 129.