Product # Price Quantity Add to cart
VD-Ant-0334-0050-50mg 220 USD
VD-Ant-0334-0250-250mg 900 USD

Antipain




Product specification

Formula: C27H44N10O6
MW: 604.71
Purity: ≥95%
Appearance: Yellow powder
Solubility:
Storage: Longterm storage temperature: -20 ± 5 °C
CAS Number: 37691-11-5
Synonyms: Chemical name: [(S)-1-Carboxy-2-phenyl-ethyl]-
carbamoyl-Arg-Val-Arg-aldehyde
Cat.number: VD-Ant-0334

Product Description

A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin (N-1000). H-1765 inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.



Product References
H.Ikezawa et al., J. Antibiot., 25, 738 (1972).
H.Suda et al., J. Antibiot., 25, 263 (1972).
S.Umezawa et al., J. Antibiot., 25, 267 (1972).
L.R.Cox et al., Cancer Res., 51, 4810 (1991).
M.Vaccari et al., Anticancer Res., 19, 589 (1999).