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VD-NP-0015-0010-10mg 55 USD
VD-NP-0015-0100-100mg 450 USD

A3, Hydrochloride




Product specification

Formula: C12H13ClN2O2S • HCl
MW: 321.2
Purity: ≥98% by TLC
Appearance: Off-white solid
Solubility: DMSO or 50% EtOH
Storage: -20°C. Hygroscopic.
CAS Number: 78957-85-4
Synonyms: N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl
Cat.number: VD-NP-0015

Product Description

A cell-permeable, reversible, and shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 µM), casein kinase II (Ki = 5.1 µM), myosin light chain kinase (Ki = 7.4 µM), protein kinase A (Ki = 4.3 µM), protein kinase C (Ki = 47 µM), and protein kinase G (Ki = 3.8 µM).



Product References
Inagaki, M., et al. 1986. Mol. Pharmacol. 29, 577. Turner, E.J.H., et al. 2003. Br. J. Haematol. 120, 894.