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Ac-YVAD-pNA (CAS 149231-66-3)




Product specification

Formula: C29H36N6O10
MW: 628.6
Purity: >=95% by HPLC
Appearance: White to off-white powder.
Solubility: DMSO. Dilute with buffer pH 7.5.
Storage: -20°C. Protect from light.
CAS Number: 149231-66-3
Synonyms: Ac-Tyr-Val-Ala-Asp-pNA
Cat.number: VD-NP-0063

Product Description

Sequence is a modification of pro-interleukin-1β Asp-116 cleavage site for caspase-1. Similar to Ac-YVAD-AMC but cleavage is monitored colorimetrically at 405nm.



Product References
1. N.A. Thornberry, et al.; Nature 356, 768 (1992).
2. L.A. Reiter; Int. J. Pept. Protein Res. 43, 87 (1994).
3. N.A. Thornberry; Meth. Enzymol. 244, 615 (1994).